.50 Action Express

From Gunpedia

The .50 Action Express (.50 AE) is a .50 caliber rebated-rim handgun cartridge built specifically for the Desert Eagle, being much more powerful than the .44 Magnum cartridge and the .357 Magnum cartridge (both of which were also designed for the Desert Eagle).

The .50 AE is recognized for its sheer power and recoil. A Desert Eagle chambered in .50 AE is the most powerful semi-automatic handgun in the world, but because of its large size, only 7 rounds are chambered in a flush magazine. Said rounds are also quite expensive and despite the hype, it is not a reliable cartridge due to its immense recoil and the tendency for the firearm to send the shell flying when ejected.

Other firearms chambered for the .50 AE include the AMT AutoMag V, LAR Grizzly Win Mag, Freedom Arms model 555, Magnum Research BFR.